Phosphatidylethanolamines Modified by γ-Ketoaldehyde (γKA) Induce Endoplasmic Reticulum Stress and Endothelial Activation

Peroxidation of plasma lipoproteins has been implicated in the endothelial cell activation and monocyte adhesion that initiate atherosclerosis, but the exact mechanisms underlying this activation remain unclear. Lipid peroxidation generates lipid aldehydes, including the γ-ketoaldehydes (γKA), also...

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Hlavní autoři: Guo, Lilu, Chen, Zhongyi, Cox, Brian E., Amarnath, Venkataraman, Epand, Raquel F., Epand, Richard M., Davies, Sean S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Lipids
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093889/
https://ncbi.nlm.nih.gov/pubmed/21454544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.213470
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