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Epidermal Growth Factor (EGF) Ligand Release by Substrate-specific A Disintegrin and Metalloproteases (ADAMs) Involves Different Protein Kinase C (PKC) Isoenzymes Depending on the Stimulus

The dysregulation of EGF family ligand cleavage has severe consequences for the developing as well as the adult organism. Therefore, their production is highly regulated. The limiting step is the ectodomain cleavage of membrane-bound precursors by one of several a disintegrin and metalloprotease (AD...

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Main Authors: Dang, Michelle, Dubbin, Karen, D'Aiello, Antonio, Hartmann, Monika, Lodish, Harvey, Herrlich, Andreas
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093846/
https://ncbi.nlm.nih.gov/pubmed/21454702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.187823
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