Hyaluronan Facilitates Transforming Growth Factor-β1-dependent Proliferation via CD44 and Epidermal Growth Factor Receptor Interaction

Fibroblast proliferation is an early feature of progressive tissue fibrosis and is largely regulated by the cytokine transforming growth factor-β1 (TGF-β1). In the oral mucosa, fibroblasts have a unique phenotype and demonstrate healing with no fibrosis/scarring. Our previous studies show that where...

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Autors principals: Meran, Soma, Luo, Dong Dong, Simpson, Russell, Martin, John, Wells, Alan, Steadman, Robert, Phillips, Aled O.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093837/
https://ncbi.nlm.nih.gov/pubmed/21454519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.226563
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