Age-Related Changes in Pericellular Hyaluronan Organization Leads to Impaired Dermal Fibroblast to Myofibroblast Differentiation

We have previously demonstrated that transforming growth factor-β1 (TGF-β1)-mediated fibroblast-myofibroblast differentiation is associated with accumulation of a hyaluronan (HA) pericellular coat. The current study demonstrates failure of fibroblast-myofibroblast differentiation associated with in...

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Detalhes bibliográficos
Main Authors: Simpson, Russell M.L., Meran, Soma, Thomas, David, Stephens, Philip, Bowen, Timothy, Steadman, Robert, Phillips, Aled
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774056/
https://ncbi.nlm.nih.gov/pubmed/19808648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090045
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