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Control of Central and Peripheral Tolerance by Aire

The negative selection of self-reactive thymocytes depends on the induction of tissue-specific antigens by medullary thymic epithelial cells. The autoimmune regulator (Aire) protein plays an important role in turning on these antigens, and the absence of even one Aire-induced tissue-specific antigen...

詳細記述

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書誌詳細
主要な著者: Metzger, Todd C., Anderson, Mark S.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093413/
https://ncbi.nlm.nih.gov/pubmed/21488892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2011.01008.x
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