Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+ tumor-derived cells

High grade gliomas (HGGs) are characterized by resistance to radiotherapy and chemotherapy. Targeting Rad51-dependent homologous recombination repair may be an effective target for chemo- and radiosensitization. In this study we assessed the role of Rad51-dependent repair on sensitivity to radiation...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Short, Susan C., Giampieri, Silvia, Worku, Mulugeta, Alcaide-German, Marisa, Sioftanos, George, Bourne, Sara, Lio, Ka Ian, Shaked-Rabi, Maya, Martindale, Christine
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093331/
https://ncbi.nlm.nih.gov/pubmed/21363882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor010
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky