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Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+ tumor-derived cells
High grade gliomas (HGGs) are characterized by resistance to radiotherapy and chemotherapy. Targeting Rad51-dependent homologous recombination repair may be an effective target for chemo- and radiosensitization. In this study we assessed the role of Rad51-dependent repair on sensitivity to radiation...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093331/ https://ncbi.nlm.nih.gov/pubmed/21363882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor010 |
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