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Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren

AIM: The aim of this study was to investigate the effects of orange juice and apple juice on the pharmacokinetics and pharmacodynamics of aliskiren. METHODS: In a randomized crossover study, 12 healthy volunteers ingested 200 ml of orange juice, apple juice or water three times daily for 5 days. On...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tapaninen, Tuija, Neuvonen, Pertti J, Niemi, Mikko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093077/
https://ncbi.nlm.nih.gov/pubmed/21204914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03898.x
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