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Using Biological Knowledge to Uncover the Mystery in the Search for Epistasis in Genome-Wide Association Studies

The search for the missing heritability in genome-wide association studies (GWAS) has become an important focus for the human genetics community. One suspected location of these genetic effects is in gene-gene interactions, or epistasis. The computational burden of exploring gene-gene interactions i...

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Detalles Bibliográficos
Autor Principal: Ritchie, Marylyn D.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092784/
https://ncbi.nlm.nih.gov/pubmed/21158748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2010.00630.x
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