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Incorporating biological knowledge in the search for gene × gene interaction in genome-wide association studies

We sought to find significant gene × gene interaction in a genome-wide association analysis of rheumatoid arthritis (RA) by performing pair-wise tests of interaction among collections of single-nucleotide polymorphisms (SNPs) obtained by one of two methods. The first method involved screening the re...

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Hlavní autoři: Manning, Alisa K, Ngwa, Julius Suh, Hendricks, Audrey E, Liu, Ching-Ti, Johnson, Andrew D, Dupuis, Josée, Cupples, L Adrienne
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795984/
https://ncbi.nlm.nih.gov/pubmed/20018077
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