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Using biological networks to search for interacting loci in genome-wide association studies

Genome-wide association studies have identified a large number of single-nucleotide polymorphisms (SNPs) that individually predispose to diseases. However, many genetic risk factors remain unaccounted for. Proteins coded by genes interact in the cell, and it is most likely that certain variants main...

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Bibliografische gegevens
Hoofdauteurs: Emily, Mathieu, Mailund, Thomas, Hein, Jotun, Schauser, Leif, Schierup, Mikkel Heide
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2986645/
https://ncbi.nlm.nih.gov/pubmed/19277065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.15
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