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An Efficient Genome-Wide Multilocus Epistasis Search

There has been a continuing interest in approaches that analyze pairwise locus-by-locus (epistasis) interactions using multilocus association models in genome-wide data sets. In this paper, we suggest an approach that uses sure independence screening to first lower the dimension of the problem by co...

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Publicat a:Genetics
Autors principals: Kärkkäinen, Hanni P., Li, Zitong, Sillanpää, Mikko J.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649656/
https://ncbi.nlm.nih.gov/pubmed/26405029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.182444
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