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Frequency of Germline PTEN Mutations in Differentiated Thyroid Cancer

BACKGROUND: Differentiated thyroid cancer (DTC) is seen in 3%–10% of individuals carrying a germline PTEN mutation. Patients with PTEN mutations are at risk for additional neoplasms as are their affected offspring. However, the frequency of PTEN mutations among DTC cases has not been systematically...

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Detalhes bibliográficos
Main Authors: Nagy, Rebecca, Ganapathi, Shireen, Comeras, Ilene, Peterson, Charissa, Orloff, Mohammed, Porter, Kyle, Eng, Charis, Ringel, Matthew D., Kloos, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092722/
https://ncbi.nlm.nih.gov/pubmed/21417916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2010.0365
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