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The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

PURPOSE OF REVIEW: The vertebrate cap’n’collar family transcription factor Nrf2 and its invertebrate homologs SKN-1 (in worms) and CncC (in flies) function as master mediators of antioxidant and detoxification responses and regulators of the cellular redox state. Nrf2 controls gene expression progra...

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Main Authors: Sykiotis, Gerasimos P., Habeos, Ioannis G., Samuelson, Andrew V., Bohmann, Dirk
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092636/
https://ncbi.nlm.nih.gov/pubmed/21102319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MCO.0b013e32834136f2
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