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Alzheimer's disease neurofibrillary degeneration: pivotal and multifactorial

Independent of the aetiology, AD (Alzheimer's disease) neurofibrillary degeneration of abnormally hyperphosphorylated tau, a hallmark of AD and related tauopathies, is apparently required for the clinical expression of the disease and hence is a major therapeutic target for drug development. Ho...

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Detalhes bibliográficos
Main Authors: Iqbal, Khalid, Wang, Xiaochuan, Blanchard, Julie, Liu, Fei, Gong, Cheng-Xin, Grundke-Iqbal, Inge
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092440/
https://ncbi.nlm.nih.gov/pubmed/20658985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0380962
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