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Phosphorylated AKT Expression is Associated with PIK3CA Mutation, Low Stage and Favorable Outcome in 717 Colorectal Cancers

BACKGROUND: AKT (AKT1, AKT2, and AKT3) is a downstream effector of phosphatidylinositide-3-kinase (PI3K) and plays crucial roles in protein synthesis, cellular metabolism, survival, and proliferation. The PI3K/AKT pathway is commonly activated in human cancers and recognized as a potential target fo...

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Detaylı Bibliyografya
Asıl Yazarlar:	Baba, Yoshifumi, Nosho, Katsuhiko, Shima, Kaori, Hayashi, Marika, Meyerhardt, Jeffrey A., Chan, Andrew T., Giovannucci, Edward, Fuchs, Charles S., Ogino, Shuji
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	2010
Konular:	Article
Online Erişim:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3092033/ https://ncbi.nlm.nih.gov/pubmed/21425139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25630
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Phosphorylated AKT Expression is Associated with PIK3CA Mutation, Low Stage and Favorable Outcome in 717 Colorectal Cancers

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