An OBSL1-Cul7(Fbxw8) Ubiquitin Ligase Signaling Mechanism Regulates Golgi Morphology and Dendrite Patterning

The elaboration of dendrites in neurons requires secretory trafficking through the Golgi apparatus, but the mechanisms that govern Golgi function in neuronal morphogenesis in the brain have remained largely unexplored. Here, we report that the E3 ubiquitin ligase Cul7(Fbxw8) localizes to the Golgi c...

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Detalhes bibliográficos
Main Authors: Litterman, Nadia, Ikeuchi, Yoshiho, Gallardo, Gilbert, O'Connell, Brenda C., Sowa, Mathew E., Gygi, Steven P., Harper, J. Wade, Bonni, Azad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091842/
https://ncbi.nlm.nih.gov/pubmed/21572988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001060
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