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Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis

BACKGROUND: Among its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating retinoic acid receptor (RAR)-mediated transcription. RAR is thought to bind the genome constitutively, and only induce transcription in the presenc...

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Detalhes bibliográficos
Main Authors: Mahony, Shaun, Mazzoni, Esteban O, McCuine, Scott, Young, Richard A, Wichterle, Hynek, Gifford, David K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091300/
https://ncbi.nlm.nih.gov/pubmed/21232103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-1-r2
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