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Rings of Charge within the Extracellular Vestibule Influence Ion Permeation of the 5-HT(3)A Receptor

The determinants of single channel conductance (γ) and ion selectivity within eukaryotic pentameric ligand-gated ion channels have traditionally been ascribed to amino acid residues within the second transmembrane domain and flanking sequences of their component subunits. However, recent evidence su...

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Bibliografski detalji
Glavni autori: Livesey, Matthew R., Cooper, Michelle A., Lambert, Jeremy J., Peters, John A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091210/
https://ncbi.nlm.nih.gov/pubmed/21454663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.219618
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