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Rings of Charge within the Extracellular Vestibule Influence Ion Permeation of the 5-HT(3)A Receptor
The determinants of single channel conductance (γ) and ion selectivity within eukaryotic pentameric ligand-gated ion channels have traditionally been ascribed to amino acid residues within the second transmembrane domain and flanking sequences of their component subunits. However, recent evidence su...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3091210/ https://ncbi.nlm.nih.gov/pubmed/21454663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.219618 |
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