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Ion permeation and conduction in a human recombinant 5-HT(3) receptor subunit (h5-HT(3A))

1. A human recombinant homo-oligomeric 5-HT(3) receptor (h5-HT(3A)) expressed in a human embryonic kidney cell line (HEK 293) was characterized using the whole-cell recording configuration of the patch clamp technique. 2. 5-HT evoked transient inward currents (EC(50) = 3.4 μm; Hill coefficient = 1.8...

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Autors principals: Brown, A M, Hope, A G, Lambert, J J, Peters, J A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230823/
https://ncbi.nlm.nih.gov/pubmed/9508827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.653bs.x
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