Spatial distribution, kinetics, signaling and cytokine production during homeostasis driven proliferation of CD4+ T cells

During recovery from lymphopenia, the naïve T-cells undergo homeostasis driven proliferation (HDP) and acquire a memory phenotype. The HDP of T-cells requires signals derived from T-cell-receptor, p56lck kinase, IL-7R and IL-15R. However, the role of other signaling molecules during HDP of CD4+ T-ce...

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Hauptverfasser: Sharma, Deepak, Kumar, S. Santosh, Checker, Rahul, Raghu, Rashmi, Khanam, Shazia, Krishnan, Sunil, Sainis, Krishna Balaji
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090723/
https://ncbi.nlm.nih.gov/pubmed/19447493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.04.019
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