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Involvement of ERK-Nrf-2 Signaling in Ionizing Radiation Induced Cell Death in Normal and Tumor Cells

Prolonged oxidative stress favors tumorigenic environment and inflammation. Oxidative stress may trigger redox adaptation mechanism(s) in tumor cells but not normal cells. This may increase levels of intracellular antioxidants and establish a new redox homeostasis. Nrf-2, a master regulator of batte...

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Bibliografiske detaljer
Main Authors: Patwardhan, Raghavendra S., Checker, Rahul, Sharma, Deepak, Sandur, Santosh K., Sainis, Krishna B.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679038/
https://ncbi.nlm.nih.gov/pubmed/23776571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065929
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