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Plumbagin Inhibits Proliferative and Inflammatory Responses of T Cells Independent of ROS Generation But by Modulating Intracellular Thiols
Plumbagin inhibited activation, proliferation, cytokine production, and graft-versus-host disease in lymphocytes and inhibited growth of tumor cells by suppressing nuclear factor-κB (NF-κB). Plumbagin was also shown to induce reactive oxygen species (ROS) generation in tumor cells via an unknown mec...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065107/ https://ncbi.nlm.nih.gov/pubmed/20564204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22620 |
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