The ER stress factor XBP1s prevents amyloid-β neurotoxicity

Alzheimer's disease (AD) is an incurable neurodegenerative disorder clinically characterized by progressive cognitive impairment. A prominent pathologic hallmark in the AD brain is the abnormal accumulation of the amyloid-β 1–42 peptide (Aβ), but the exact pathways mediating Aβ neurotoxicity re...

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Bibliografische gegevens
Hoofdauteurs: Casas-Tinto, Sergio, Zhang, Yan, Sanchez-Garcia, Jonatan, Gomez-Velazquez, Melisa, Rincon-Limas, Diego E., Fernandez-Funez, Pedro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2011
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090193/
https://ncbi.nlm.nih.gov/pubmed/21389082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr100
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