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The ER stress factor XBP1s prevents amyloid-β neurotoxicity
Alzheimer's disease (AD) is an incurable neurodegenerative disorder clinically characterized by progressive cognitive impairment. A prominent pathologic hallmark in the AD brain is the abnormal accumulation of the amyloid-β 1–42 peptide (Aβ), but the exact pathways mediating Aβ neurotoxicity re...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3090193/ https://ncbi.nlm.nih.gov/pubmed/21389082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr100 |
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