Indolizidine (−)-235B′ and related structural analogs: discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [(3)H]dopamine release

Although several therapeutic agents are available to aid in tobacco smoking cessation, relapse rates continue to be high, warranting the development of alternative pharmacotherapies. Nicotine-evoked dopamine release from its presynaptic terminals in the central nervous system leads to reward which m...

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Detalhes bibliográficos
Main Authors: Pivavarchyk, Marharyta, Smith, Andrew M., Zhang, Zhenfa, Zhou, Dejun, Wang, Xu, Toyooka, Naoki, Tsuneki, Hiroshi, Sasaoka, Toshiyasu, McIntosh, J. Michael, Crooks, Peter A., Dwoskin, Linda P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089962/
https://ncbi.nlm.nih.gov/pubmed/21371454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2011.02.018
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