Common genetic variation at BARD1 is not associated with Breast cancer risk in BRCA1 or BRCA2 mutation carriers

BACKGROUND: Inherited BRCA1 and BRCA2 (BRCA1/2) mutations confer elevated breast cancer risk. Knowledge of factors that can improve breast cancer risk assessment in BRCA1/2 mutation carriers may improve personalized cancer prevention strategies. METHODS: A cohort of 5,546 BRCA1 and 2,865 BRCA2 mutat...

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Autors principals: Spurdle, Amanda B., Marquart, Louise, McGuffog, Lesley, Healey, Sue, Sinilnikova, Olga, Wan, Fei, Chen, Xiaoqing, Beesley, Jonathan, Singer, Christian F, Dressler, Anne-Catharine, Gschwantler-Kaulich, Daphne, Blum, Joanne L., Tung, Nadine, Weitzel, Jeff, Lynch, Henry, Garber, Judy, Easton, Douglas F., Peock, Susan, Cook, Margaret, Oliver, Clare T., Frost, Debra, Conroy, Don, Evans, D. Gareth, Lalloo, Fiona, Eeles, Ros, Izatt, Louise, Davidson, Rosemarie, Chu, Carol, Eccles, Diana, Selkirk, Christina G., Daly, Mary, Isaacs, Claudine, Stoppa-Lyonnet, Dominique, Sinilnikova, Olga M., Buecher, Bruno, Belotti, Muriel, Mazoyer, Sylvie, Barjhoux, Laure, Verny-Pierre, Carole, Lasset, Christine, Dreyfus, Hélène, Pujol, Pascal, Collonge-Rame, Marie-Agnès, Rookus, Matti A., Verhoef, Senno, Kriege, Mieke, Hoogerbrugge, Nicoline, Ausems, Margreet G.E.M., van Os, Theo A., Wijnen, Juul, Devilee, Peter, Meijers-Heijboer, Hanne E.J., Blok, Marinus J., Heikkinen, Tuomas, Nevanlinna, Heli, Jakubowska, Anna, Lubiński, Jan, Huzarski, Tomasz, Byrski, Tomasz, Durocher, Francine, Couch, Fergus J., Lindor, Noralane M., Wang, Xianshu, Thomassen, Mads, Domchek, Susan, Nathanson, Kate, Caligo, MA, Jernström, Helena, Liljegren, Annelie, Ehrencrona, Hans, Karlsson, Per, Ganz, Patricia A., Olopade, Olufunmilayo I., Tomlinson, Gail, Neuhausen, Susan, Antoniou, Antonis C., Chenevix-Trench, Georgia, Rebbeck, Timothy R.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089675/
https://ncbi.nlm.nih.gov/pubmed/21393566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-10-0909
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