HLA-DQ Genotype Is Associated with Accelerated Small Bowel Transit in Patients with Diarrhea-Predominant Irritable Bowel Syndrome

BACKGROUND: Colonic transit (CT) is accelerated in 46% of patients with diarrhea-predominant irritable bowel syndrome (IBS-D). Improvement in IBS-D with gluten withdrawal is associated with HLA-DQ2 positivity; the mechanism of improvement is unclear. OBJECTIVE: To determine if HLA-DQ2 or HLA-DQ8 pos...

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Autores principales: Vazquez-Roque, Maria I., Camilleri, Michael, Carlson, Paula, McKinzie, Sanna, Murray, Joseph A., Brantner, Tricia L., Burton, Duane D., Zinsmeister, Alan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089653/
https://ncbi.nlm.nih.gov/pubmed/21490506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MEG.0b013e328346a56e
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