Association of HLA-DQ gene with bowel transit, barrier function, and inflammation in irritable bowel syndrome with diarrhea

Patients with irritable bowel syndrome (IBS) with diarrhea (IBS-D) carrying human leukocyte antigen (HLA)-DQ2/8 genotypes benefit from gluten withdrawal. Our objective was to compare gastrointestinal barrier function, mucosal inflammation, and transit in nonceliac IBS-D patients and assess associati...

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Bibliografiske detaljer
Main Authors: Vazquez-Roque, Maria I., Camilleri, Michael, Smyrk, Thomas, Murray, Joseph A., O'Neill, Jessica, Carlson, Paula, Lamsam, Jesse, Eckert, Deborah, Janzow, Denise, Burton, Duane, Ryks, Michael, Rhoten, Deborah, Zinsmeister, Alan R.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Neuroregulation and Motility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532460/
https://ncbi.nlm.nih.gov/pubmed/23042942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00294.2012
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