Effect of Increased Bile Acid Synthesis or Fecal Excretion in Irritable Bowel Syndrome-Diarrhea

OBJECTIVES: Approximately 25% of patients with irritable bowel syndrome-diarrhea (IBS-D) have increased total fecal bile acids (BA) and serum C4 (surrogate for BA synthesis). BA synthesis-related genes (KLB and FGFR4) are associated with colonic transit (CT) in IBS-D. Our aims were: (i) to compare p...

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Publicado en:Am J Gastroenterol
Autores principales: Camilleri, Michael, Busciglio, Irene, Acosta, Andres, Shin, Andrea, Carlson, Paula, Burton, Duane, Ryks, Michael, Rhoten, Deborah, Lamsam, Jesse, Lueke, Alan, Donato, Leslie J., Zinsmeister, Alan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994231/
https://ncbi.nlm.nih.gov/pubmed/25070056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2014.215
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