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Atomistic simulations reveal bubbles, kinks and wrinkles in supercoiled DNA

Although DNA is frequently bent and supercoiled in the cell, much of the available information on DNA structure at the atomistic level is restricted to short linear sequences. We report atomistic molecular dynamics (MD) simulations of a series of DNA minicircles containing between 65 and 110 bp whic...

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Detalhes bibliográficos
Main Authors: Mitchell, J. S., Laughton, C. A., Harris, Sarah A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089460/
https://ncbi.nlm.nih.gov/pubmed/21247872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1312
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