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Molecular Dynamics Simulations of Duplex Stretching Reveal the Importance of Entropy in Determining the Biomechanical Properties of DNA

Advances in nanomanipulation techniques have made it possible to measure the response of an individual biomolecule to a force applied in the laboratory. Experiments that stretch a single molecule of duplex DNA have been difficult to interpret theoretically, particularly as the major changes in molec...

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Main Authors: Harris, Sarah A., Sands, Zara A., Laughton, Charles A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Biophysical Society 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305225/
https://ncbi.nlm.nih.gov/pubmed/15626714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.046912
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