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The Mechanical Properties of RNA-DNA Hybrid Duplex Stretched by Magnetic Tweezers

RNA can anneal to its DNA template to generate an RNA-DNA hybrid (RDH) duplex and a displaced DNA strand, termed R-loop. RDH duplex occupies up to 5% of the mammalian genome and plays important roles in many biological processes. The functions of RDH duplex are affected by its mechanical properties,...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Zhang, Chen, Fu, Hang, Yang, Yajun, Zhou, Erchi, Tan, Zhijie, You, Huijuan, Zhang, Xinghua
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350079/
https://ncbi.nlm.nih.gov/pubmed/30635125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.12.005
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