Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs

Herein, we study the nanomechanical characteristics of single DNA molecules in the presence of DNA binders, including intercalating agents (ethidium bromide and doxorubicin), a minor groove binder (netropsin) and a typical alkylating damaging agent (cisplatin). We have used magnetic tweezers manipul...

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Bibliografski detalji
Glavni autori: Salerno, Domenico, Brogioli, Doriano, Cassina, Valeria, Turchi, Diana, Beretta, Giovanni Luca, Seruggia, Davide, Ziano, Roberto, Zunino, Franco, Mantegazza, Francesco
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Molecular Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978368/
https://ncbi.nlm.nih.gov/pubmed/20601682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq597
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