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Nanomechanics of Diaminopurine-Substituted DNA
2,6-diaminopurine (DAP) is a nucleobase analog of adenine. When incorporated into double-stranded DNA (dsDNA), it forms three hydrogen bonds with thymine. Rare in nature, DAP substitution alters the physical characteristics of a DNA molecule without sacrificing sequence specificity. Here, we show th...
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| Veröffentlicht in: | Biophys J |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6403411/ https://ncbi.nlm.nih.gov/pubmed/30795872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.01.027 |
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