Nanomechanics of G-quadruplexes within the promoter of the KIT oncogene

G-quadruplexes (G4s) are tetrahelical DNA structures stabilized by four guanines paired via Hoogsteen hydrogen bonds into quartets. While their presence within eukaryotic DNA is known to play a key role in regulatory processes, their functional mechanisms are still under investigation. In the presen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Buglione, Enrico, Salerno, Domenico, Marrano, Claudia Adriana, Cassina, Valeria, Vesco, Guglielmo, Nardo, Luca, Dacasto, Mauro, Rigo, Riccardo, Sissi, Claudia, Mantegazza, Francesco
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2021
Pynciau:
Molecular Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096272/
https://ncbi.nlm.nih.gov/pubmed/33849064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab079
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