Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs

Herein, we study the nanomechanical characteristics of single DNA molecules in the presence of DNA binders, including intercalating agents (ethidium bromide and doxorubicin), a minor groove binder (netropsin) and a typical alkylating damaging agent (cisplatin). We have used magnetic tweezers manipul...

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Bibliografiske detaljer
Main Authors: Salerno, Domenico, Brogioli, Doriano, Cassina, Valeria, Turchi, Diana, Beretta, Giovanni Luca, Seruggia, Davide, Ziano, Roberto, Zunino, Franco, Mantegazza, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978368/
https://ncbi.nlm.nih.gov/pubmed/20601682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq597
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