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Mapping the phase diagram of the writhe of DNA nanocircles using atomistic molecular dynamics simulations
We have investigated the effects of duplex length, sequence, salt concentration and superhelical density on the conformation of DNA nanocircles containing up to 178 base pairs using atomistic molecular dynamics simulation. These calculations reveal that the partitioning of twist and writhe is govern...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2248748/ https://ncbi.nlm.nih.gov/pubmed/17984075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm891 |
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