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Simulation of DNA Supercoil Relaxation

Several recent single-molecule experiments observe the response of supercoiled DNA to nicking endonucleases and topoisomerases. Typically in these experiments, indirect measurements of supercoil relaxation are obtained by observing the motion of a large micron-sized bead. The bead, which also serves...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Ivenso, Ikenna D., Lillian, Todd D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880802/
https://ncbi.nlm.nih.gov/pubmed/27224483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.03.041
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