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Understanding mechanisms underlying human gene expression variation with RNA sequencing

Understanding the genetic mechanisms underlying natural variation in gene expression is a central goal of both medical and evolutionary genetics, and studies of expression quantitative trait loci (eQTLs) have become an important tool for achieving this goal(1). Although all eQTL studies so far have...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pickrell, Joseph K., Marioni, John C., Pai, Athma A., Degner, Jacob F., Engelhardt, Barbara E., Nkadori, Everlyne, Veyrieras, Jean-Baptiste, Stephens, Matthew, Gilad, Yoav, Pritchard, Jonathan K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089435/
https://ncbi.nlm.nih.gov/pubmed/20220758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08872
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