DNaseI sensitivity QTLs are a major determinant of human expression variation

The mapping of expression quantitative trait loci (eQTLs) has emerged as an important tool for linking genetic variation to changes in gene regulation(1-5). However, it remains difficult to identify the causal variants underlying eQTLs and little is known about the regulatory mechanisms by which the...

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Main Authors: Degner, Jacob F., Pai, Athma A., Pique-Regi, Roger, Veyrieras, Jean-Baptiste, Gaffney, Daniel J., Pickrell, Joseph K., De Leon, Sherryl, Michelini, Katelyn, Lewellen, Noah, Crawford, Gregory E., Stephens, Matthew, Gilad, Yoav, Pritchard, Jonathan K.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501342/
https://ncbi.nlm.nih.gov/pubmed/22307276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10808
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