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Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data
Motivation: Next-generation sequencing has become an important tool for genome-wide quantification of DNA and RNA. However, a major technical hurdle lies in the need to map short sequence reads back to their correct locations in a reference genome. Here, we investigate the impact of SNP variation on...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788925/ https://ncbi.nlm.nih.gov/pubmed/19808877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp579 |
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