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Noisy Splicing Drives mRNA Isoform Diversity in Human Cells

While the majority of multiexonic human genes show some evidence of alternative splicing, it is unclear what fraction of observed splice forms is functionally relevant. In this study, we examine the extent of alternative splicing in human cells using deep RNA sequencing and de novo identification of...

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Detaylı Bibliyografya
Asıl Yazarlar: Pickrell, Joseph K., Pai, Athma A., Gilad, Yoav, Pritchard, Jonathan K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000347/
https://ncbi.nlm.nih.gov/pubmed/21151575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001236
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