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The Genetic and Mechanistic Basis for Variation in Gene Regulation

It is now well established that noncoding regulatory variants play a central role in the genetics of common diseases and in evolution. However, until recently, we have known little about the mechanisms by which most regulatory variants act. For instance, what types of functional elements in DNA, RNA...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Pai, Athma A., Pritchard, Jonathan K., Gilad, Yoav
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287341/
https://ncbi.nlm.nih.gov/pubmed/25569255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004857
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