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The Genetic and Mechanistic Basis for Variation in Gene Regulation

It is now well established that noncoding regulatory variants play a central role in the genetics of common diseases and in evolution. However, until recently, we have known little about the mechanisms by which most regulatory variants act. For instance, what types of functional elements in DNA, RNA...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Pai, Athma A., Pritchard, Jonathan K., Gilad, Yoav
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287341/
https://ncbi.nlm.nih.gov/pubmed/25569255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004857
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