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Gβγ Activates GSK3 to Promote LRP6-Mediated β-Catenin Transcriptional Activity
Evidence from Drosophila and cultured cell studies support a role for heterotrimeric G proteins in Wnt signaling. Wnt inhibits the degradation of the transcriptional regulator β-catenin. We screened the α subunits of major families of recombinant G protein subunits and Gβγ subunits in a Xenopus egg...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3088111/ https://ncbi.nlm.nih.gov/pubmed/20460648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000647 |
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