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Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells

Cohesin, a hetero-tetrameric complex of SMC1, SMC3, Rad21 and Scc3, associates with chromatin after mitosis and holds sister chromatids together following DNA replication. Following DNA damage, cohesin accumulates at and promotes the repair of DNA double-strand breaks. In addition, phosphorylation o...

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Bibliografiske detaljer
Main Authors: Bauerschmidt, Christina, Woodcock, Michael, Stevens, David L., Hill, Mark A., Rothkamm, Kai, Helleday, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Academic Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087432/
https://ncbi.nlm.nih.gov/pubmed/21056556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2010.10.021
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