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Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells

Cohesin, a hetero-tetrameric complex of SMC1, SMC3, Rad21 and Scc3, associates with chromatin after mitosis and holds sister chromatids together following DNA replication. Following DNA damage, cohesin accumulates at and promotes the repair of DNA double-strand breaks. In addition, phosphorylation o...

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Detalhes bibliográficos
Main Authors: Bauerschmidt, Christina, Woodcock, Michael, Stevens, David L., Hill, Mark A., Rothkamm, Kai, Helleday, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087432/
https://ncbi.nlm.nih.gov/pubmed/21056556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2010.10.021
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