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The shape of the radiation dose response for DNA double-strand break induction and repair

DNA double-strand breaks are among the most deleterious lesions induced by ionising radiation. A range of inter-connected cellular response mechanisms has evolved to enable their efficient repair and thus protect the cell from the harmful consequences of un- or mis-repaired breaks which may include...

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Detalhes bibliográficos
Main Authors: Barnard, Stephen, Bouffler, Simon, Rothkamm, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616853/
https://ncbi.nlm.nih.gov/pubmed/23522792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-4-1
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