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A Bayesian response-adaptive covariate-balanced randomization design with application to a leukemia clinical trial

We propose a Bayesian response-adaptive covariate-balanced randomization design for multiple-arm comparative clinical trials. The goal of the design is to skew the allocation probability to more efficacious treatment arms, while also balancing the distribution of the covariates across the arms. In p...

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Detalhes bibliográficos
Main Authors: Yuan, Ying, Huang, Xuelin, Liu, Suyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086983/
https://ncbi.nlm.nih.gov/pubmed/21432894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.4218
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